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Scientific Papers: Examined from a Metabolic Perspective     

Cannabis and Neuropsychiatric Disorders: An Updated Review 5/6/20

ROS in Cancer Therapy: The Bright Side of the Moon

Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment 3/29/20

Chronic Activation of Endogenous Angiotensin-Converting Enzyme 2 Protects Diabetic Rats from Cardiovascular Autonomic Dysfunction 3/29/20

Activation of TNFR1 ectodomain shedding by mitochondrial Ca2+ determines the severity 3/26/2020

Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain 3/26/2020

Effects of Obesity on Bone Metabolism 2/19/20

Mitochondrial Fission Forms a Positive Feedback Loop With Cytosolic Calcium Signaling Pathway to Promote Autophagy in Hepatocellular Carcinoma Cells 2/1820

Feasibility, Safety, and Beneficial Effects of MCT-Based Ketogenic Diet for Breast Cancer Treatment: A Randomized Controlled Trial Study 2/15/20

Metabolic Sensor AMPK Directly Phosphorylates RAG1 Protein and Regulates V(D)J Recombination 2/15/20

AMPK: Master Metabolic Regulator  2/15/20

Salidroside Ameliorates Diabetic Nephropathy in Rats by Activating Renal AMPK/SIRT1 Signaling Pathway 2/11/20

Mitigation of Glucolipotoxicity-Induced Apoptosis, Mitochondrial Dysfunction, and Metabolic Stress by N-Acetyl Cysteine in Pancreatic β-Cells 2/9/20

An AMPK-caspase-6 Axis Controls Liver Damage in Nonalcoholic Steatohepatitis 2/9/20

Nutritional omega-3 Deficiency Abolishes Endocannabinoid-Mediated Neuronal Functions 2/6/20

Activation of AMP-activated Protein Kinase by Compound 991 Protects Osteoblasts From Dexamethasone 1/22/20

Effects of Cannabinoid Receptor Type 2 in Respiratory Syncytial Virus Infection in Human Subjects and Mice  2/1/2020

Curcumin Ameliorates Severe Influenza Pneumonia via Attenuating Lung Injury and Regulating Macrophage Cytokines Production 2/1/2020

Monounsaturated Fatty Acids Protect Against Palmitate-Induced Lipoapoptosis in Human Umbilical Vein Endothelial Cells

Supplementation of pyruvate prevents palmitate-induced impairment of glucose uptake in C2 myotubes

Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis 1/23/20

Fats and factors: lipid profiles associate with personality factors and suicidal history in bipolar subjects 1/22/20

Flaxseed oil increases the plasma concentrations of cardioprotective (n-3) fatty acids in humans 1/22/22

Endocannabinoids in Caenorhabditis elegans are essential for the mobilization of cholesterol from internal reserves 1/22/22

Thyroid hormone stimulates brown fat production. Brown fat is burned (autophagy) to generate heat, while reducing electron transport flowto reduce free radical production. Polyunsaturated fatty acids, as found in fish oil, function similarly. 1/21/21

Downregulation of G2/mitotic-specific cyclinB1 triggers autophagy via AMPK-ULK1-dependent signal pathway in nasopharyngeal carcinoma cells 1/21/20

Hypermethylated in cancer 1 (HIC1) mediates high glucose induced ROS accumulation in renal tubular epithelial cells by epigenetically repressing SIRT1 transcription1/20/20

Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors 1/19/2020

Mitochondrial fragmentation, elevated mitochondrial superoxide and respiratory supercomplexes disassembly is connected with the tamoxifen-resistant phenotype of breast cancer cells 1/18/20

AMPKα1 deficiency suppresses brown adipogenesis in favor of fibrogenesis during brown adipose tissue development.  1/17/20

Autophagy modulators from traditional Chinese medicine: Mechanisms and therapeutic potentials for cancer and neurodegenerative diseases. 1/17/20

Therapeutic potential of polyphenols in cardiovascular diseases: regulation of mTOR signaling pathway  1/17/20

ω3-polyunsaturated fatty acids induce cell death through apoptosis and autophagy in glioblastoma cells: in vitro and in vivo 

AICAR Induces Apoptosis and Inhibits Migration and Invasion in Prostate Cancer Cells Through an AMPK/mTOR-Dependent Pathway

Inhibits p53-Mutant Prostate Cancer Cells Growth by Activating AMPK-Dependent Pathway

PARP10 (ARTD10) modulates mitochondrial function

PARP-1 Involvement in Autophagy and Their Roles in Apoptosis of Vascular Smooth Muscle Cells under Oxidative Stress

The oncogenic role of CB2 in the progression of non-small-cell lung cancer

Curcumin Inhibits Aerobic Glycolysis in Hepatic Stellate Cells Associated with Activation of Adenosine Monophosphate-activated Protein Kinase

Curcumin modulates cannabinoid receptors in liver fibrosis in vivo and inhibits extracellular matrix expression in hepatic stellate cells by suppressing cannabinoid receptor type-1 in vitro

The autophagy inhibitor chloroquine targets cancer stem cells in triple negative breast cancer by inducing mitochondrial damage and impairing DNA break repair

CDK9 Inhibition Induces a Metabolic Switch that Renders Prostate Cancer Cells Dependent on Fatty Acid Oxidation

Metformin enhances the radiosensitizing effect of cisplatin in non-small cell lung cancer cell lines with different cisplatin sensitivities 

Metformin inhibits both oleic acid-induced and CB1R receptor agonist-induced lipid accumulation in Hep3B cells:The preliminary report

Molecular mechanisms of autophagy in regulating renal aging and interventional effects of Chinese herbal medicine

Relationship between thiol-disulphide homeostasis and visual evoked potentials in patients with multiple sclerosis

Extremely rapid increase in fatty acid transport and intramyocellular lipid accumulation but markedly delayed insulin resistance after high fat feeding in rats.

Increased oxidative phosphorylation in response to acute and chronic DNA damage

Cannabinoids ameliorate cerebral dysfunction following liver failure via AMP-activated protein kinase.

Estrogen prevents articular cartilage destruction in a mouse model of AMPK deficiency via ERK-mTOR pathway

© drbob 2018